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Topic: Science
Number of pages / Number of words: 3 / 615
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In further laboratory research, it was discovered that effective use of insulin by the brain reduced overeating and promoted the full-feeling discussed before, which supports the evidence of insulin-resistance as a cause of obesity.

After this discovery, research began on how to rid insulin-resistance in the brain, and medicinal advancements have been made...


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Although not yet approved by the FDA, metformin has been discovered. This is a medication that increases insulin and leptin sensitivity that was developed to treat type-2 diabetics but has proven to reduce weight in non-diabetic, morbidly obese adolescents by sensitizing the body to insulin by increasing the activity of the tyrosine kinas (the body's main insulin receptor), which in turn activates insulin-signaling pathways...


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