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AFP results detect 20%-25% if carried out alone (Cuckle 1984), tests combining more than one measure detected 48%-91%. A study using AFP and HCG detected 90% of cases in women over 35 and 43% in women under 30, it also found that detection rates were better when the test was performed before week 17 (Gouldie et al 1995)...
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A study performed shows that the mean iliac angle is 60o for normal foetuses and 75o in foetuses with Down syndrome, by measuring the iliac angle in foetuses the liklihood of Down syndrome can be worked out, for example if the iliac angle is 50o the liklihood is 1/588 of the foetus having trisomy 21, if however the angle is 80o then the chance is 1/50...
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