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Topic: Science
Number of pages / Number of words: 6 / 1468
Essay's paper body

In many tissues - muscle being a prime example - the

major transporter used for uptake of glucose (called GLUT4) is made available in the

plasma membrane through the action of insulin.

In the absence

of insulin, GLUT4 glucose

transporters are present in cytoplasmic vesicles,

where they useless for transporting glucose...


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When blood levels

of insulin decrease and insulin receptors are no

longer occupied, the glucose transporters are

recycled back into the cytoplasm.

The animation to the right depicts how

insulin signalling leads to translocation of

glucose transporters from the cytoplasm into

the plasma membrane, allowing glucose

(small blue balls) to enter the cell...


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