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| Topic: |
Science
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| Number of pages / Number of words: |
33 / 8996 |
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However, this risk is greatly outweighed by the reduction in risk conferred by treating the primary cancer in the vast majority of cases.
In this paper, we will concentrate on a particular branch of phototherapy, with promising and exciting developments in the treatment of serious and malignant skin-related conditions...
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Light photons are absorbed by the photosensitiser, which generate reactive species e.g. singlet oxygen (1O2) or the hydroxyl radical, which are cytotoxic. In this case, the subsequent oxidation of proteins, amino acids and lipids leads to cell necrosis and apoptosis. The key characteristic of these photosensitisers is that they are highly selective, in that they penetrate and accumulate in the tumour cells or in the endothelium of newly formed vessels while, in the most part, avoiding the surrounding healthy tissue...
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