Buy custom Excretion And Elimination Of Toxicants And Their Metabolites
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| Topic: |
Science
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| Number of pages / Number of words: |
4 / 1078 |
Essay's paper body
The
faster the rate of glomerular filtration , the faster the polar xenobiotics are
eliminated from the body. Other factors that affect the rate of elimination
include: dose of the xenobiotic, the rate pf absorption
, and the ability to bind
to proteins as well as the polarity of the compound.
In comparison lipophilic compounds will cross the cell membrane with more
ease...
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Due to their lipohpillic properties they will follow the their
concentration gradient across the membrane of the tubules and are ,therefore,
easily retained by the body. If a lipophilic compound is metabolized to a more
polar state then it is more easily metabolized. Another important factor that
will determine excretion by the kidneys will be the pH of the environment...
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