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It was decided that the best route for the production of butadiene or isoprene was from butanol or isoamyl alcohol. This initiated an investigation into the possibility of producing the compounds by means of a microbial fermentation. In 1911 Fernbach isolated a culture which was able to ferment potatoes, but not maize starch, to produce butanol...
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In 1912 Weizmann terminated the connection with Strange and Graham td. but continued his research at Manchester University . He had concluded that the production of butanol or isoamyl alcohol by fermentation was essential for the success of the synthetic rubber process, and although he was not a microbiologist, he set about training himself to become one...
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