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Topic: Psychology
Number of pages / Number of words: 4 / 942
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As damage spreads, cells lose their ability to do their jobs well. Eventually, they die.

Inside the Brain: An Interactive Tour

Learn how the brain works and how

Alzheimer's affects it.

Back to top

The role of plaques and tangles

Two abnormal structures called plaques and tangles are prime suspects in damaging and killing nerve cells...


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Plaques and tangles were among the abnormalities that Dr. Alois Alzheimer saw in the brain of Auguste D., although he called them different names.

Plaques build up between nerve cells. They contain deposits of a protein fragment called beta-amyloid (BAY-tuh AM-uh-loyd). Tangles are twisted fibers of another protein called tau (rhymes with “wow”)...


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