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However, they are carriers of the disease, which means they can pass the defective gene on to their children. The cause of this disease is not the sickle cell itself but its short life span. Once red blood cells leave your bone marrow they will live for about 120 days before they die and need to be replaced but sickle cells die after only 10 to 20 days...
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This causes difficulty for your body to produce enough replacements. The result is a chronic shortage of red blood cells, known as anemia.
Bone marrow transplant offers the only potential cure for sickle cell anemia. But very few people have a suitable donor for transplant. As a result, treatment for sickle cell anemia is usually aimed at avoiding crises, relieving symptoms and preventing complications...
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