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Sickle cell disease is also associated with significant mortality. Among children, the primary causes of mortality are bacterial infections and stroke. In adults, it is more difficult to attribute specific causes to mortality, but it appears that individuals with more indicative disease are at risk for early mortality...
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Some patients lead fairly normal lives, attending school and work with only occasional pain episodes and only slowly progressive organ damage. Treatments, such as penicillin prophylaxis, have been developed that can significantly reduce the rate of disease and mortality of sickle cell disease patients...
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