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Topic: Science
Number of pages / Number of words: 28 / 7727
Essay's paper body

The bacteria then travel to lungs and

establish an infection (1). In the lungs they ?rst encounter

alveolar macrophage, which has the ability to destroy most

potential invaders. However, M. tuberculosis has the extra-

ordinary ability to persist and even replicate in this extremely

hostile environment, where most other pathogens would perish...


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tuberculosis seems to have evolved e?ective strategies to

survive most of the macrophage killing mechanisms.

In most common clinical pattern of tuberculosis, T

lymphocytes get activated after infection and this causes

in?ltration of activated macrophages to the site of infection.

These lymphocytes arrest the organism inside a granuloma-

tous lesion called a tubercle...


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