Buy custom Vasospastic cardiac ischemia
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Science
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| Number of pages / Number of words: |
16 / 4386 |
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Ischemia from vasospasm suggests a defect in the vasodilating mechanism. The main components regulating vascular tone are the endothelium, the vascular smooth muscle and the autonomic nervous system8. The role of each will now be discussed.
Endothelial dysfunction
The role of endothelium in vascular tone regulation is well recognised...
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Endothelial derived relaxing factors such as nitric oxide and prostaglandins are important local vasodilators. Nitric oxide also inhibits production of endothelin, a long acting and potent endothelium derived vasoconstrictor. Endothelial dysfunction is, therefore, the logical target of investigation for the mechanism behind vasospasm...
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