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It
would take just the amount they estimated to maintain the blood sugar level.
In 1986 the first experiment started. A lot of immune-suppresent drugs
are needed so the foreign tissue would not be rejected. These drugs are risky,
though, so the experiment was performed on patients who have had kidney
transplants and are already on these drugs...
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They decided that the best place to
place the islets was into the portal vein leading to the pancreas. This would
give the islets nourishment from the beginning and would be less risky than
placing them directly into the pancreas.
The results were encouraging. Subjects were given 400,000 islets and the
grafts worked...
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