Buy custom The effect of drugs, toxins, and other molecules on synapse and synapse transmission.
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| Topic: |
Science
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| Number of pages / Number of words: |
6 / 1480 |
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Below are the steps involved in a cholinergic transmission:
Step 1: The action potential travels down to the axon terminal of the presynaptic neuron. Each axon terminal becomes swollen, forming a postsynaptic knob. There is a depolarisation of the presynaptic membrane as a result from the action potential...
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This depolarisation causes and increases in the permeability to sodium and calcium ions. The presynaptic knob is then filled with membrane-bound vesicles; each filled with ACh. Calcium ions then flood into the presynaptic knob by diffusion.
Step 2: The influx of calcium ions triggers the exocytosis of the synaptic vesicles...
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