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| Topic: |
Science
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| Number of pages / Number of words: |
8 / 2097 |
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This was done to avoid toxic effect of PAA on biomass growth. The addition of vegetable oils or corn steep liquor significantly improved the penicillin production by P.chrysogenum. The replacement of lactose with the continuous addition of glucose or sucrose did not change antibiotic production, but resulted in a financial advantage...
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Corn steep liquor represent major nitrogen source.
About 65% of the carbon is metabolized for cellular maintenance, 20?25% for growth and 10?12% for penicillin production. Sugar and precursor are fed continuously and the sugar is also used to help regulate the pH of the fermentation to between 6.4?6...
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