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Topic: Science
Number of pages / Number of words: 12 / 3330
Essay's paper body

1) and tested their

pathogenicity in mice. Among nine single-gene

reassortant viruses, each containing one gene

segment from HK486 virus and the remaining

segments from HK483 virus, only those possessing

the PB2 (HK3/6PB2) or HA-227I

(HK3/6HA227I) gene from the HK486 virus

were appreciably attenuated (MLD50, 1...


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Moreover, although more than 106 PFU/g of

virus was detected at 6 days after infection in

the lungs of mice infected with either HK3/

6PB2 or HK3/6HA227I virus (Table 1), virus

was not recovered from other nonrespiratory

organs (with the exception of the heart in mice

infected with HK3/6PB2 virus)...


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