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| Topic: |
Science
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| Number of pages / Number of words: |
39 / 10715 |
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It is believed that Zn2+ has a functional role in the hexamer formation and that this process facilitates the conversion of proinsulin to insulin and storage of the hormone. Traditional insulin is hexameric in most of the highly concentrated preparations used for therapy. When the hormone is absorbed and the concentration falls to physiological levels (nanomolar), the hormone dissociates into monomers, and the monomer is most likely the biologically active form of insulin...
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Traditional insulin is hexameric in most of the highly concentrated preparations used for therapy. When the hormone is absorbed and the concentration falls to physiological levels (nanomolar), the hormone dissociates into monomers, and the monomer is most likely the biologically active form of insulin...
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