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Topic: Science
Number of pages / Number of words: 2 / 434
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Bone atrophy and misalignment cause visible deformaties and disrupt the articulation of opposing bones causing muscle atrophy and imbalance and possibly partial dislocation

4th stage: calcification of the fibrous tissue resulting in bony ankylosis and total immobility.


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This auto-immune reaction causes inflammation of the joints, particularly the synovial membrane that lines them. If the process continues, damage to the cartilage and other soft tissue can cause joint deformities.

The effects differ from person to person. Most people first become aware of pain, swelling and stiffness in the small joints of the hands or feet...


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