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Topic: Science
Number of pages / Number of words: 8 / 2026
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Such fears may be particularly warranted in patients with the most advanced disease, in whom the sympathetic nervous system may play a supportive (rather than deleterious) role to support cardiac contractility.11 In this regard, it is noteworthy that previous studies of ?-blockade in heart failure generally evaluated only patients with mild to moderate symptoms3 4 5 6 7 8 12 13 14 or mild to moderate hemodynamic abnormalities (ejection fraction >0...


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Such fears may be particularly warranted in patients with the most advanced disease, in whom the sympathetic nervous system may play a supportive (rather than deleterious) role to support cardiac contractility.11 In this regard, it is noteworthy that previous studies of ?-blockade in heart failure generally evaluated only patients with mild to moderate symptoms3 4 5 6 7 8 12 13 14 or mild to moderate hemodynamic abnormalities (ejection fraction >0...


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