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Buy custom An Outline of the General Scentific Insights that Microbial Genome Sequencing Can and Has Provided

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Topic: Science
Number of pages / Number of words: 10 / 2635
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This paper depicted four possible generalised benefits of improved microbial genome understanding in the world of medicine;

? A better understanding of microbial pathogenesis.

? New approaches to diagnosis.

? Insights in to human biology and disease.

? Drug and vaccine development.

Now we know entire genomes, the process of screening for virulence genes is becoming a possibility, but we must first identify those virulence genes, this process may be a lengthy one by conventional methods, that is, by ‘knocking out’ genes in animal models and monitoring them, or the more efficient method labelled “mutagenesis”8 where large pools of genes are knocked out...


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This process has already advanced our pathogenic understanding as it has already identified the virulence genes for Salmonella typhimurium, Staphylococcus aureus, and Vibrio cholerae.8-10.

Jenks also notes that general medicinal diagnosis approaches are yet to catch up with the microbial genome knowledge currently available, detection of microbial infections still rely heavily upon morphology with a few exceptions of more dangerous organisms such as Chlamydia trachomatis and Myobacterium tuberculosis...


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