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Topic: Science
Number of pages / Number of words: 4 / 871
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The so-called IL-4 "knock-out" mice, specifically bred without the gene for IL-4 and thus apparently impervious to the conversion toward TH2, were reported in 1993 to be resistant to MAIDS precisely because they lacked any IL-4. But rather than the absence of IL-4 accounting for the mice's apparent resistance to disease, it turns out that it might well have been an unintentional genetic difference in the knock-out mice which resulted from the special IL-4 knock-out breeding...


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The so-called IL-4 "knock-out" mice, specifically bred without the gene for IL-4 and thus apparently impervious to the conversion toward TH2, were reported in 1993 to be resistant to MAIDS precisely because they lacked any IL-4. But rather than the absence of IL-4 accounting for the mice's apparent resistance to disease, it turns out that it might well have been an unintentional genetic difference in the knock-out mice which resulted from the special IL-4 knock-out breeding...


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