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This receptor is expressed only on platelets and is key in mediating the binding of fibrinogen to platelets, only when activated in clotting. Tc99m is then bound to these abnormal sites. Unbound Tc99m Apcitide is cleared rapidly predominantly in urine or bile. Imaging can begin in 10 minutes and is usually complete in 60-90 minutes...
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Imaging can begin in 10 minutes and is usually complete in 60-90 minutes. Sensitivity, Specificity, NPV etc. is approximately 88-91%.
Talifer JNM, 1997; 38:123P (Abs. No. 459)
Jnm 1999 40,11P (Abs. No. 4)
Tallilefer R, Radiolabeled Peptides in the Detection of Deep Venous Thrombosis,Seminars in Nucloear Medicine,Vol XXXI, No 2 (April),2001: pp 102-123
Tc99m Apcitide is useful in imaging DVT in:
Obese patients, patients with orthopedic casts, trauma, acute DVT in calf/pelvis, to differentiate recurrent acute from non acute DVT, and equivocal venographic examinations or US...
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